Pearls in Paediatrics Renal Transplantation. A Discussion on Debatable Issues

Renal transplantation is the treatment of first choice for paediatrics chronic kidney disease. Owing to the tremendous impact of chronic kidney disease on general health and growth of the children which would not be alleviated by other modalities of renal replacement therapy, kidney transplantation must be provided for all the patients regardless to the underlying aetiology of renal disease. The commonest cause of chronic kidney disease is congenital anomaly of urinary tract. It instigates pre-transplant corrective interventions to ascertain successful transplantation. Herein, we elucidate the different aspects of paediatrics kidney transplantations, elaborating on unique preparatory measures considered in the context of congenital bladder dysfunction and obstructive uropathy. Furthermore, we discussed peculiar issues relevant to the surgical procedure for implanting renal allograft for paediatrics recipients. Moreover, we addressed contentious issues pertinent to post transplantation varied immune suppression protocols and its related potential complications. Lastly, we formulated an alleged protocol for complicated cases of paediatrics kidney transplantation.

Keywords: Paediatrics Transplantation, Bladder Dysfunction, Immune Suppression Protocol.